Pakistan were all out for 260 in 47.2 overs with Babar Azam (64) and Khushdil Shah (69) scoring half-centuries but the hosts never looked in the hunt.
Aiming for their second Cricket World Cup title, Pakistan will be led by Babar Azam and are armed with a strong batting unit that includes Fakhar Zaman, Imam-Ul-Haq, Mohammed Rizwan, Iftikhar Ahmed, and Salman Agha.
Babar Azam's approach drew heavy criticism from fans
Pakistan have made four changes to the side for the second Test against England after resting senior cricketers including former captain Babar Azam from the rest of the series.
Pakistan skipper Babar Azam sent a strong message to his team as they go into a crucial set of matches ahead of the ICC ODI World Cup.
India captain Rohit Sharma played down concerns around his fitness after a crucial group A match of the Champions Trophy against Pakistan. Despite a brief period off the field during the Pakistan innings, Rohit assured that his hamstring was "okay." Meanwhile, Virat Kohli's century led India to a six-wicket victory, putting them on the verge of a semifinal berth.
Fast bowler Khurram Shahzad and Mohammad Abbas have been named in Pakistan's team for the first Test starting on Thursday in Centurion - the first red-ball assignment for newly-appointed interim coach Aqib Javed.
PCB newly selected Chief Selector Inzamam Ul Haq announced squads for the upcoming ACC Men's Asia Cup and the three-match One-Day International series against Afghanistan.
West Indies were bowled out for 163 before they fought back to dismiss Pakistan for 154 shortly before the close of play.
Virat Kohli anchored a tricky chase with an unbeaten 100.
Imam combined with Saud Shakeel to steady the ship
IMAGES from the ICC World Cup match played between Pakistan and The Netherlands in Hyderabad on Friday.
West Indies secured their first Test win in Pakistan since 1990 after beating the hosts by 120 runs in the second match.
De Leede ripped through the Pakistan line-up taking 4-62 and Colin Ackerman claimed 2-39 after the Netherlands won the toss and decided to bowl, but Rizwan (68) and Shakeel (68) ensured the Asian side made 286 in 49 overs.
The Pakistan cricket team arrived in Dubai on Thursday for their crucial Champions Trophy clash against India, hoping to bounce back after their opening loss to New Zealand.
It was Rizwan's 120-run stand with Saud Shakeel that allowed Pakistan to recover from a shaky start and post 286.
New Zealand clinched the tri-nation title by beating hosts Pakistan by five wickets in the final in Karachi on Friday to give them a major boost ahead of next week's Champions Trophy.
Pakistan's bowlers had gone for plenty against India and they will look to comeback strongly in what is a virtual semi-final against Sri Lanka.
Pakistan beat England by nine wickets in the deciding third Test to win the series 2-1 in Rawalpindi on Saturday.
The home side are chasing a modest target of 148 after bowling out Pakistan for 237 and if they win will be assured a place in the WTC final at Lord's.
Shaheen Afridi also missed the last two Tests against England in October.
IMAGES from the Champions Trophy Group A match played between Pakistan and New Zealand at the National Stadium in Karachi on Wednesday.
IMAGES from the ICC World Cup match between Pakistan and South Africa, in Chennai, on Friday.
Pakistan's Shan Masood is likely to be retained captain for the upcoming home Test series against England, while Babar Azam is also assured of keeping his white-ball captaincy when the team flies to Australia and South Africa later this year.
Pakistan selectors want Babar Azam to open in CT, hope star batter will emulate Sachin Tendulkar
Chasing 185 for victory, Bangaldesh were well-placed on 42 for no loss in seven overs before rain forced the players off the field in the post-tea session.
Pakistan are traditionally good against spinners but Babar Azam and Co. would take the likes of promising Dunith Wellalage and company lightly at their peril.
Keeping in mind the forecast for rain and overcast conditions, Pakistan team management is likely to field a pace-heavy bowling unit against Bangladesh in the first Test scheduled between August 21 and 25 at Rawalpindi.
Shafique and Salman pummel Sri Lanka, Pakistan eye series sweep
Pakistan needed 178 runs to win the second Test and sweep the series
Saim Ayub and Khurram Shahzad received their debut call-ups to Pakistan's squad for the three-match Test series against Australia.
Bangladesh registered their first ever Test win over Pakistan after spinners Mehidy Hasan Miraz and Shakib Al Hasan bowled them to a memorable 10-wicket victory.
Bosch's knock, which included 15 boundaries, helped South Africa to 301 all out at tea and a handy lead over the tourists, who scored 211 in their first innings.
Leg-spinner Shah's selection was subject to the 35-year-old clearing a fitness test, chief selector Mohammad Wasim said in a statement.
Faheem and Hasan Ali are expected to regain full fitness before the second Test (12-16 March).
'As far as my comeback (from injury) is concerned, I will hopefully return to competitive cricket in a month'
IMAGES from Day 3 of the 2nd Test played between Pakistan and England in Multan, on Thursday.
A desperate Pakistan will be wary of a competent group of Afghanistan spinners' ability to strike hard on an often-gripping Chepauk pitch when the teams meet in the World Cup match in Chennai on Monday
'The team expected me to bowl fast and used me as an attacking option. I tried to repay the faith by sticking to my strengths and staying humble.'
They are afraid of grass pitches: Basit Ali's surprising take on Pakistan batters ahead of England Test series